In situ hybridization of hamsterlhuman hybrids with biotinylated human genomic D N A has revealed that human chromosomal DNA can integrate into the hamster genome and is not always cytologically detectable. This finding helps t o explain why discordancy can arise in gene mapping by failing to recogn
Direct nonradioactive in situ hybridization of somatic cell hybrid DNA to human lymphocyte chromosomes
β Scribed by T. Kievits; P. Devilee; J. Wiegant; M. C. Wapenaar; C. J. Cornelisse; G. J. B. van Ommen; P. L. Pearson
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 611 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0196-4763
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Atomic force microscopy (AFM) permits one to generate a topographic representation of the sample under investigation with high spatial resolution. We assumed that cytochemical staining techniques, which yield reaction products which can be discriminated from the surrounding material on basis of thei
An unambiguous and rapid characterization of amplified DNA sequences in tumor cells is important for the understanding of neoplastic progression. This study was conducted t o evaluate the potential of fluorescence in situ hybridization (FISH) t o identify such amplified DNA sequences in human tumor