𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Direct introduction of a benzoyloxy substituent at the C-4 position of β-lactams

✍ Scribed by Christopher J. Easton; Stephen G. Love

Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
208 KB
Volume
27
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

The copper-promoted reaction of B-lactams with t-butyl perbenzoate results in benzoyloxylation of the azetidin-2-one ring at the C-4 position.

There is no competing reaction at the C-3 position, but reaction at exocyclic carbon a to nitrogen competes with ring substitution.

📜 SIMILAR VOLUMES

ChemInform Abstract: Direct Introduction
ChemInform Abstract: Direct Introduction of Nucleophilic Carbanions to the γ-Position of Na-Boc-Protected Nb-Tryptophylpyridinium Salts Without Electron-Withdrawing Substituents at the β-Position.
✍ Pirjo Hanhinen; Tiina Putkonen; Mauri Lounasmaa 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Direct Introduction of a Boryl Substitue
Direct Introduction of a Boryl Substituent into the 2-Position of Azulene: Application of the Miyaura and Smith Methods to Azulene
✍ Kei Kurotobi; Masato Miyauchi; Katsuto Takakura; Toshihiro Murafuji; Yoshikazu S 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 90 KB

## Abstract The 4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolanyl group was directly introduced into the 2‐positions of azulenes with high selectivity by the C−H activation method with use of iridium catalysis. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)