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Carbohydrate triflates: Introduction of substituents by double inversion at C-4″ of kanamycin A

✍ Scribed by Rainer Albert; Karl Dax; Arnold E. Stütz


Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
355 KB
Volume
132
Category
Article
ISSN
0008-6215

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The copper-promoted reaction of B-lactams with t-butyl perbenzoate results in benzoyloxylation of the azetidin-2-one ring at the C-4 position. There is no competing reaction at the C-3 position, but reaction at exocyclic carbon a to nitrogen competes with ring substitution.