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Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors

✍ Scribed by Bajocchi, Gianluigi; Feldman, Sanford H.; Crystal, Ronald G.; Mastrangeli, Andrea


Book ID
109915365
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
796 KB
Volume
3
Category
Article
ISSN
1061-4036

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## Abstract ## Background In previous studies, we showed that gene activated matrices (GAMs) containing nonviral vectors successfully deliver genes to neurons after optic nerve and spinal cord injury. In the present study, we evaluated whether adenoviral vectors delivered within a GAM increase the