A model system for in vivo gene transfer into the central nervous system using an adenoviral vector
โ Scribed by Davidson, Beverly L.; Allen, Edward D.; Kozarsky, Karen F.; Wilson, James M.; Roessler, Blake J.
- Book ID
- 109915363
- Publisher
- Nature Publishing Group
- Year
- 1993
- Tongue
- English
- Weight
- 604 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1061-4036
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Background Canavan disease (CD) is an autosomal recessive leukodystrophy characterized by deยฎciency of aspartoacylase (ASPA) and increased levels of N-acetylaspartic acid (NAA) in brain and body ยฏuids, severe mental retardation and early death. Gene therapy has been attempted in a number of children
## Abstract We have used the __Sleeping Beauty__ (__SB__) transposable element to generate transgenic __Xenopus laevis__ with expression of green fluorescent protein (GFP) in vascular endothelial cells using the frog flkโ1 promoter. This is the first characterization of a __SB__โgenerated transgeni