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Direct construction of novel dispiro heterocycles through 1,3-dipolar cycloaddition of azomethine ylides

โœ Scribed by Anshu Dandia; Anuj K. Jain; Dharmendra S. Bhati


Book ID
113929840
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
470 KB
Volume
52
Category
Article
ISSN
0040-4039

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A facile one-pot synthesis of novel steroidal dispiropyrrolidines has been accomplished by 1,3-dipolar cycloaddition reaction of various azomethine ylides derived from isatin/acenaphthenequinone/ninhydrin and sarcosine with various estrone derivatives as dipolarophiles, in good yield. The effect of