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Ionic liquid mediated 1,3-dipolar cycloaddition of azomethine ylides: a facile and green synthesis of novel dispiro heterocycles

โœ Scribed by Renuka Jain; Kanti Sharma; Deepak Kumar

Book ID
113930607
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
292 KB
Volume
53
Category
Article
ISSN
0040-4039

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โœ Shanmugavel Uma Maheswari; Kamaraj Balamurugan; Subbu Perumal; Perumal Yogeeswar ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 582 KB

A facile 1,3-dipolar cycloaddition of azomethine ylide generated in situ from the reaction of 1,3-thiazolane-4-carboxylic acid and isatin to 2-arylidene-1,3-indanediones furnished novel dispiro-oxindolylpyrrolothiazoles regio-and stereo-selectively in moderate to good yields (60-92%). In vitro antit