Direct catalytic asymmetric anti-selective Mannich-type reactions
✍ Scribed by Ibrahem, Ismail; C?rdova, Armando
- Book ID
- 120510093
- Publisher
- Royal Society of Chemistry
- Year
- 2006
- Tongue
- English
- Weight
- 306 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1359-7345
- DOI
- 10.1039/b602221a
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📜 SIMILAR VOLUMES
## Abstract **Weich hilft hart**: Die Titelreaktion zwischen Thioamiden und __N__‐(Diphenylphosphinoyl)iminen nutzt die kooperative Katalyse einer weichen Lewis‐Säure und einer harten Brønsted‐Base, um Thioamid‐Kohlenstoff‐Pränucleophile in Mannich‐Produkte zu überführen (siehe Schema). Folgereakti
## Abstract **Taking the reins**: The title transformation of thioamides and __N__‐diphenylphosphinoyl imines is described. By harnessing the power of cooperative catalysis between a soft Lewis acid and a hard Brønsted base, thioamide carbon pronucleophiles can furnish Mannich products (see scheme)