## Abstract The asymmetric aldol‐Tishchenko reaction of aromatic aldehydes with aliphatic and aromatic ketones has been developed as an efficient strategy for the synthesis of __anti__‐1,3‐diols in good yield with high diastereocontrol and good levels of enantioselectivity. This domino‐type reactio
✦ LIBER ✦
Direct Asymmetric Aldol—Tishchenko Reaction.
✍ Scribed by Jacek Mlynarski
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 18 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The development of a direct catalytic asymmetric aldol–Tishchenko reaction and the nature of its catalyst are described. An aldol–Tishchenko reaction of various propiophenone derivatives with aromatic aldehydes was promoted by [LaLi~3~(binol)~3~] (LLB), and reactivity and enantioselecti