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Direct arylations on water: synthesis of 2,5-disubstituted oxazoles balsoxin and texaline

✍ Scribed by Ohnmacht, Stephan A.; Mamone, Patrizia; Culshaw, Andrew J.; Greaney, Michael F.

Book ID
115479557
Publisher
Royal Society of Chemistry
Year
2008
Tongue
English
Weight
581 KB
Volume
10
Category
Article
ISSN
1359-7345

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ChemInform Abstract: Direct Arylations o
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A novel and direct synthesis of 2-alkyl-
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A direct and efficient method for the preparation of 2-alkyl-5-aryt disubstituted oxazoles was realized by reaction of aromatic oC-methyl ketones with various aliphatic nitriles in the presence ofTl(OTf)3.