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First Halogen Dance Reaction on Oxazoles. Synthesis of 4,5-Disubstituted 2-Phenyloxazoles.

✍ Scribed by Peter Stanetty; Markus Spina; Marko D. Mihovilovic

Publisher
John Wiley and Sons
Year
2005
Weight
20 KB
Volume
36
Category
Article
ISSN
0931-7597

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Synthesis of 2,4- and 2,5-Disubstituted
Synthesis of 2,4- and 2,5-Disubstituted Oxazoles via Metal- Catalyzed Cross-Coupling Reactions
✍ Carla M. Counceller; Chad C. Eichman; Nicolas Proust; James P. Stambuli 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 180 KB 👁 1 views

## Abstract The rapid synthesis of 2,4‐ and 2,5‐disubstituted oxazoles __via__ metal‐catalyzed cross‐coupling reactions is reported. The 4‐ or 5‐position of the corresponding 4‐ or 5‐halogenated 2‐butylthiooxazoles was successfully functionalized __via__ Suzuki–Miyaura, Sonogashira and Stille cross