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Dipolar addition reactions of nitrile oxides. VII. A new general method of synthesis of 3,5-disubstituted 1,2,4-oxadiazoles.

✍ Scribed by P. Rajagopalan

Publisher
Elsevier Science
Year
1969
Tongue
French
Weight
127 KB
Volume
10
Category
Article
ISSN
0040-4039

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✦ Synopsis

We would like to report that aliphatic and aromatic nitrile oxides (I), as exemplified by pivalonitrile oxide and I-chlorobenzonitrile oxide respectively, react with methyl imidates (II) at room temperature (in absolute ether) to yield 1.2,4-oxadiazoles of the type III (See Table ).

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