By x-ray crystallography of the 116 epimer, toxins C3 and C4 are shown to be 2lsuIfo-N-Ihydroxysaxitoxin-llo-and Ilf%-~ydroxysulfate, confirming the position and identity of the 3 substituents which, with the parent compound, form the array of 12 saxitoxins found in Protogonyaulax.
Dinoflagellate neurotoxins related to saxitoxin: Structure and latent activity of toxins B1 and B21
β Scribed by F.E. Koehn; S. Hall; C.Fix Wichmann; H.K. Schnoes; P.B. Reichardt
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 166 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Toxins Bl and B2 from cultured dinoflagellates of the genus FrotogonyauZaa: are shown to be the carbamoyl-N-sulfo derivatives of saxitoxin and neosaxitoxin, the structures confirmed by synthesis from the corresponding decarbamoyl toxins.
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## Abstract A ceramide monohexoside, acanthacerebroside B^1b,2a)^, was purified from the waterβinsoluble lipid fraction of the chloroform/methanol extract of the starfish __Asterina pectinifera__ MΓΌller et Troschel using reversedβphase HPLC. A new method for identification of components of the cera