Increased expression and activity of MMP-9 in C-reactive protein- induced human THP-1 mononuclear cells is related to activation of nuclear factor kappa-B

FGF-1-induced matrix metalloproteinase-9

FGF-1-induced matrix metalloproteinase-9 expression in breast cancer cells is mediated by increased activities of NF-κB and activating protein-1

✍ Gina Lungu; Lina Covaleda; Odete Mendes; Heidi Martini-Stoica; George Stoica 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 365 KB

## Abstract Matrix metalloproteinase‐9 (MMP‐9) plays a critical role in tumor invasion and metastasis. Here, we investigate the effect of fibroblast growth factor‐1 (FGF‐1) on the expression of MMP‐9 in ENU1564, an ethyl‐__N__‐nitrosourea‐induced rat mammary adenocarcinoma cell line. We observed th