Toxins Bl and B2 from cultured dinoflagellates of the genus FrotogonyauZaa: are shown to be the carbamoyl-N-sulfo derivatives of saxitoxin and neosaxitoxin, the structures confirmed by synthesis from the corresponding decarbamoyl toxins.
Dinoflagellate neurotoxins related to saxitoxin: Structures of toxins C3 and C4, and confirmation of the structure of neosaxitoxin
β Scribed by S. Hall; S.D. Darling; G.L. Boyer; P.B. Reichardt; H.-W. Liu
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- French
- Weight
- 181 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
By x-ray crystallography of the 116 epimer, toxins C3 and C4 are shown to be 2lsuIfo-N-Ihydroxysaxitoxin-llo-and Ilf%-~ydroxysulfate, confirming the position and identity of the 3 substituents which, with the parent compound, form the array of 12 saxitoxins found in Protogonyaulax.
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