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Dimerizer-Mediated Regulation of Gene Expression In Vitro

✍ Scribed by Rivera, V. M.; Berk, L.; Clackson, T.


Book ID
121871702
Publisher
Cold Spring Harbor Laboratory Press
Year
2012
Tongue
English
Weight
392 KB
Volume
2012
Category
Article
ISSN
1940-3402

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## Abstract The CD44 adhesion receptor is silenced in highly malignant neuroblastomas (NBs) with __MYCN__ amplification. Because its functional expression is associated with decreased tumorigenic properties, __CD44__ behaves as a tumor suppressor gene in NB and other cancers. Given that the precise