## Abstract Diketopiperazines (DKPs), the smallest cyclic peptides, represent an important class of biologically active natural products and their research has been fundamental to many aspects of peptide chemistry. The advent of combinatorial chemistry has revived interest in DKPs for two reasons:
Diketopiperazines in Peptide and Combinatorial Chemistry
โ Scribed by Peter M. Fischer
- Book ID
- 101942725
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 48 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Abstract
For Abstract see ChemInform Abstract in Full Text.
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Diketopiperazines, which are cyclic dipeptides, are often formed by a side reaction of solid-phase peptide synthesis. Using the new "Backbone Amide Linker," this chemistry can be conveniently harnessed for the intentional preparation of diketopiperazines. These products will be useful scaffolds for
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