Dihydroisobenzofurans and isoindolines by intramolecular inverse Diels-Alder reactions of pyridines
β Scribed by Marek Biedrzycki; Dick A. de Bie; Henk C. van der Plas
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 432 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0040-4020
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π SIMILAR VOLUMES
Pyrimidines carrying a dienophilic side-chain at the 2 or 5 position undergo intramolecular Diels-Alder reactions to give heterocyclic annelated pyridines. Inverse electron demand Diels-Alder reactions of heterocyclic azadienes with electron-rich dienophiles are well documented'. Recently, the intra
## Abstract Pyrimidine alkynes can be transformed into the corresponding annulated pyridines efficiently in flow. The superheating of organic solvents far beyond their boiling point enables toxic and difficult to workup solvents such as nitrobenzene or chlorobenzene, which are usually employed for
Syntheses of several 6,6,6-tricyclic condensed pyridines and pyrazines utilizing intramolecular Diels-Alder reactions of 1,2,4-triazines with alkyne and nitrile dienophiles are detailed. The cyclizations are facilitated by the presence 01 conformationally restrictive planar aromatic rings in the cha
## Abstract For Abstract see ChemInform Abstract in Full Text.