Novel ringtransformations of pyrimidines and pyridines by intramolecular inverse electron demand Diels-Alder reactions
β Scribed by A. E. Frissen; A. T. M. Marcelis; G. Geurtsen; D. A. de Bie; H. C. van der Plas
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 178 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0165-0513
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π SIMILAR VOLUMES
Pyrimidines carrying a dienophilic side-chain at the 2 or 5 position undergo intramolecular Diels-Alder reactions to give heterocyclic annelated pyridines. Inverse electron demand Diels-Alder reactions of heterocyclic azadienes with electron-rich dienophiles are well documented'. Recently, the intra
## Abstract Pyrimidine alkynes can be transformed into the corresponding annulated pyridines efficiently in flow. The superheating of organic solvents far beyond their boiling point enables toxic and difficult to workup solvents such as nitrobenzene or chlorobenzene, which are usually employed for
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Imidazole and 2-phenylimidazoleundergo intramolecularcycloadditions with 1,2,4triazines tethered betweenan imidazolenitrogenand the triazinylC3 position with a trimethylene chainto producetetrahydro-l,5-naphthyridines followingloss of N2 and a nitrile.