𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Dihydrodiols and diol epoxides of dibenzo[a,i]-and [a,h]pyrene

✍ Scribed by Roland E. Lehr; Subodh Kumar; Patrick T. Cohenour; Donald M. Jerina

Publisher
Elsevier Science
Year
1979
Tongue
French
Weight
276 KB
Volume
20
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Synthesis of dihydrodiols from chrysene
Synthesis of dihydrodiols from chrysene and dibenzo[a,h]anthracene
✍ J.M. Karle; H.D. Mah; D.M. Jerina; H. Yagi πŸ“‚ Article πŸ“… 1977 πŸ› Elsevier Science 🌐 French βš– 235 KB

Numerous lines of evidence have now implicated 7,8-diol-9,10-epoxides as metabolically formed ultimate carcinogens from the environmental contaminant benzo[alpyrene. ly2 In an attempt to generalize the concept of diol epoxides3 as ultimate carcinogens, we have attempted to predict which of the sever

Radioactively labelled epoxides. part V.
Radioactively labelled epoxides. part V. Tritium labelled K-region oxides and trans-dihydrodiols of pyrene, benzo[a]pyrene and dibenz[a, h]anthracene
✍ Frans Setiabudi; Franz Oesch; Karl L. Platt πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 French βš– 296 KB

T r i t i u m l a b e l l e d K-region oxides o f pyrene, benzoCalpyrene and d i b e n z [ G ] a n t h r a c e n e have been prepared by c y c l i z a t i o n o f the corresponding t r a n s -d i h y d r o d i o l s which were obtained by r e d u c t i o n o f K-region quinones w i t h sodium b o r

Anti-diol epoxide of benzo[a]pyrene indu
Anti-diol epoxide of benzo[a]pyrene induces transient Mdm2 and p53 Ser15 phosphorylation, while anti-diol epoxide of dibenzo[a,l]pyrene induces a nontransient p53 Ser15 phosphorylation
✍ Gerd PÀÀjΓ€rvi; Bengt JernstrΓΆm; Albrecht Seidel; Ulla Stenius πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 365 KB

## Abstract The polycyclic aromatic hydrocarbons (PAHs) dibenzo[__a,l__]pyrene (DBP) and benzo[__a__]pyrene (BP) are environmental contaminants and potent carcinogens. DBP is several orders of magnitude more mutagenic/carcinogenic than BP. This can be ascribed to differences in DNA binding efficien

Inhibition of BRCA-1 expression by benzo
Inhibition of BRCA-1 expression by benzo[a]pyrene and its diol epoxide
✍ Brandon D. Jeffy; Elizabeth U. Schultz; Ornella Selmin; Jean M. Gudas; G. Tim Bo πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 364 KB

The objective of this study was to investigate whether polycyclic aromatic hydrocarbons (PAHs) contribute to the etiology of sporadic breast cancer by altering the expression of BRCA-1. Acute exposure to the PAH benzo[a]pyrene (B[a]P) inhibited in a time-and dose-dependent fashion cell proliferation