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Difluoromethylene analogues of aspartyl phosphate: the first synthetic inhibitors of aspartate semi-aldehyde dehydrogenase

✍ Scribed by Cox, Russell J.; Mayo-Martín, M. Belén; Hadfield, Andrea T.


Book ID
120237533
Publisher
Royal Society of Chemistry
Year
2001
Tongue
English
Weight
90 KB
Volume
18
Category
Article
ISSN
1359-7345

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ChemInform Abstract: Difluoromethylene A
✍ Russell J. Cox; Andrea T. Hadfield; M. Belen Mayo-Martin 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Aspartyl Phosphonates and Phosphoramidat
✍ Russell J. Cox; Jennifer S. Gibson; María Belén Mayo Martín 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 279 KB

The synthesis of methylene phosphonate, difluoromethylene phosphonate and phosphoramidate analogues of aspartyl phosphate, together with reduced analogues, is described. These compounds were shown to be effective inhibitors of aspartate-semialdehyde dehydrogenase (ASA-DH) from Escherichia coli. Howe