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Differentiation of the surface topographies of pharmaceutical excipient compacts

✍ Scribed by P. Narayan; B.C. Hancock; R. Hamel; T.S. Bergstrom; B.E. Childs; C.A. Brown

Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
819 KB
Volume
430
Category
Article
ISSN
0921-5093

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To gain a deeper understanding of the behavior of carbamazepine (CBZ) and CBZ dihydrate (DH) compacts during in vitro dissolution tests various factors were investigated: hydrate formation of CBZ, crystal morphology, surface area, and excipient influence. Dissolution tests were performed in three di