The influence of particle size on the surface roughness of pharmaceutical excipient compacts
β Scribed by P. Narayan; B.C. Hancock
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 747 KB
- Volume
- 407
- Category
- Article
- ISSN
- 0921-5093
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π SIMILAR VOLUMES
In previous papers of our research group, a linear relationship between the drug percolation threshold and the relative drug particle size (drug/excipient) has been found, in the case of the inert matrices. The objective of the present paper is to investigate the influence of the particle size on th
To gain a deeper understanding of the behavior of carbamazepine (CBZ) and CBZ dihydrate (DH) compacts during in vitro dissolution tests various factors were investigated: hydrate formation of CBZ, crystal morphology, surface area, and excipient influence. Dissolution tests were performed in three di
11), hydrophobic interaction (12, 13), secondary minimum The influence of particle size on the kinetics of slow Brownian coagulation (6-8, 14-16), slow equilibration of the surface coagulation is studied. Colloidal gold was chosen as a model syscharge during the collisions (17, 18), etc.-into tradit