## Abstract BALB/cโnu nu mice which have been injected with a congenic thymus cell suspension are able to reject skin grafts from all other strains tested. Mice injected with allogeneic H๏ฃฟ2 incompatible thymus cells do not reject skin grafts. When allogeneic, H๏ฃฟ2 compatible cells are used, grafts f
โฆ LIBER โฆ
Differentiation of T cell precursors in nude mice. Rejection of heart grafts of thymus donor strain
โ Scribed by R. Seger; K. Rogers; D. Catty
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 329 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
Thymus grafted nude mice showed no tolerance to neonatal heart grafts of thymus donor origin. This finding is in contradiction with the Jerne hypothesis on the somatic generation of immune recognition and in agreement with Bretscher's hypothesis on generalized autoimmunity.
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