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T-Cell development in the absence of a thymus: The number, the phenotype, and the functional capacity of T lymphocytes in nude mice

✍ Scribed by Chen, Wei-Feng ;Scollay, Roland ;Shortman, Ken ;Skinner, Margot ;Marbrook, John


Publisher
Wiley (John Wiley & Sons)
Year
1984
Tongue
English
Weight
751 KB
Volume
170
Category
Article
ISSN
0002-9106

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Recent findings suggest that mature T cells in the thymus may regulate the growth and differentiation of immature thymocytes. Here we use mathematical modeling and computer simulations to identify the thymocyte subsets that might serve as targets for regulation, and the processes that might be affec