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Development of the tight-skin phenotype in immune-deficient mice

โœ Scribed by Tatjana D. Dodig; Kristine T. Mack; Deborah F. Cassarino; Stephen H. Clark

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
78 KB
Volume
44
Category
Article
ISSN
0004-3591

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## BACKGROUND: The etiology of neural tube defects (NTDs) is multifactorial, with environmental and genetic determinants. Folate supplementation prevents the majority of NTDs, and a polymorphism in methylenetetrahydrofolate reductase (MTHFR) has become recognized as a genetic risk factor. The mech