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Differentiation agents enhance cholinergic characteristics of LA-N-2 human neuroblastoma cells

✍ Scribed by Richard D. Crosland


Book ID
116019092
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
702 KB
Volume
58
Category
Article
ISSN
0024-3205

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## Abstract The presence of 10^βˆ’5^ M retinoec acid (RA) in the culture medium of LA‐N‐1, a catecholamonergic cell line, and LA‐N‐2, a cholinergic cell line, enhanced their morphological differentiation. Tyrosine hydroxylase (TH) activity of the LA‐N‐1 cell was increased in the RA‐treated cells comp