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Differential stereoselectivity in the metabolism of benzo[a]pyrene and anthracene by rabbit epidermal and hepatic microsomes

✍ Scribed by Hall, Michael; Grover, Philip L.


Book ID
123472488
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
565 KB
Volume
38
Category
Article
ISSN
0304-3835

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## Abstract A rat liver microsome‐mediated bacterial mutagenicity test showed 9‐hydroxybenzo (__a__) pyrene to be significantly more effective as a pre‐mutagen than benzo (__a__) pyrene. Experiments measuring the ability of these compounds to be metabolically activated to moieties that alky late ex