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Differential responsiveness to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in sub-regions of the primate substantia nigra and striatum

✍ Scribed by J.D. Elsworth; A.Y. Deutch; D.E. Redmond Jr.; J.R. Sladek Jr.; R.H. Roth


Book ID
118342432
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
592 KB
Volume
40
Category
Article
ISSN
0024-3205

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## Abstract We assessed the presence of degenerating neurons in the substantia nigra pars compacta (SNpc) and ventral tegmental area (VTA) of parkinsonian monkeys. For this purpose, we used two histological markers of cellular death, Fluoro Jade B (FJB) staining and terminal deoxynucleotidyl transf