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Effects of treadmill exercise on behavioral recovery and neural changes in the substantia nigra and striatum of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse

✍ Scribed by Beth A. Smith; Natalie R.S. Goldberg; Charles K. Meshul


Book ID
113505554
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
981 KB
Volume
1386
Category
Article
ISSN
0006-8993

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## Abstract Physical activity has been shown to be neuroprotective in lesions affecting the basal ganglia. Using a treadmill exercise paradigm, we investigated the effect of exercise on neurorestoration. The 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP)‐lesioned mouse model provides a means t