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Differential regulation of HIF-1α prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells

✍ Scribed by Catherine L Cioffi; Xiao Qin Liu; Penelope A Kosinski; Michelle Garay; Benjamin R Bowen


Book ID
117053644
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
301 KB
Volume
303
Category
Article
ISSN
0006-291X

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## Abstract We examined how ionizing radiation (IR) delivered under either severe hypoxia (< 0.1% O~2~) or normoxia affects the expression of hypoxia inducible factor 1α (HIF‐1α) and the angiogenic factors vascular endothelial growth factor (VEGF) and angiopoietins 1, 2 and 4 in U87 human glioblast