✦ LIBER ✦

Endothelin-1 regulates hypoxia-inducible factor-1α and -2α stability through prolyl hydroxylase domain 2 inhibition in human lymphatic endothelial cells

✍ Scribed by Caprara, Valentina; Scappa, Silvia; Garrafa, Emirena; Di Castro, Valeriana; Rosanò, Laura; Bagnato, Anna; Spinella, Francesca

Book ID: 122162090
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 794 KB
Volume: 118
Category: Article
ISSN: 0024-3205
DOI: 10.1016/j.lfs.2014.02.030

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Vasohibin induces prolyl hydroxylase-med

Vasohibin induces prolyl hydroxylase-mediated degradation of hypoxia-inducible factor-1α in human umbilical vein endothelial cells

✍ Tomohiro Kozako; Noriko Matsumoto; Yukako Kuramoto; Akira Sakata; Rie Motonagare 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 1018 KB

Inhibition of Transforming Growth Factor

Inhibition of Transforming Growth Factor β1/Smad3 Signaling Decreases Hypoxia-Inducible Factor-1α Protein Stability by Inducing Prolyl Hydroxylase 2 Expression in Human Periodontal Ligament Cells

✍ Watanabe, Teppei; Yasue, Akihiro; Tanaka, Eiji 📂 Article 📅 2013 🏛 American Academy of Periodontology 🌐 English ⚖ 312 KB

Stimulation of HIF-1α, HIF-2α, and VEGF

Stimulation of HIF-1α, HIF-2α, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells

✍ Tiina M. Asikainen; Aftab Ahmad; Barbara K. Schneider; Wen-Bin Ho; Michael Arend 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 415 KB

Significance of Prolyl Hydroxylase 2 in

Significance of Prolyl Hydroxylase 2 in the Interference of Aryl Hydrocarbon Receptor and Hypoxia-Inducible Factor-1α Signaling

✍ Seifert, Anja; Katschinski, Dörthe M.; Tonack, Sarah; Fischer, Bernd; Navarrete 📂 Article 📅 2008 🏛 American Chemical Society 🌐 English ⚖ 887 KB

Inactivation of prolyl hydroxylase domai

Inactivation of prolyl hydroxylase domain (PHD) protein by epigallocatechin (EGCG) stabilizes hypoxia-inducible factor (HIF-1α) and induces hepcidin (Hamp) in rat kidney

✍ Dominador J. Manalo; Jin Hyen Baek; Paul W. Buehler; Evi Struble; Bindu Abraham; 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 691 KB

2-oxoglutarate downregulates expression

2-oxoglutarate downregulates expression of vascular endothelial growth factor and erythropoietin through decreasing hypoxia-inducible factor-1α and inhibits angiogenesis

✍ Ken Matsumoto; Shigehiko Imagawa; Naoshi Obara; Norio Suzuki; Satoru Takahashi; 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 299 KB

## Abstract In oxygenated cells, hypoxia‐inducible factor‐1 (HIF‐1) α subunits are rapidly degraded by a mechanism that involves ubiquitination by the von Hippel–Lindau tumor suppressor E3 ligase complex using 2‐oxoglutarate as a substrate. We examined the effect of 2‐oxoglutarate on the production