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Differential Purinergic Receptor Signalling in Osteoclasts and Osteoblastic Cells

โœ Scribed by Laura Chun Luo; Hesheng Yu; Jack Ferrier


Book ID
114284066
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
246 KB
Volume
9
Category
Article
ISSN
0898-6568

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P2 purinergic receptors on osteoblasts a
โœ S. Jeffrey Dixon; Stephen M. Sims ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 268 KB

Extracellular nucleotides like ATP bind to cell surface receptors (P2 purinergic receptors) in many tissues. P2X receptor subtypes are intrinsic ion channels that mediate depolarization and influx of Ca 2+ , whereas the P2Y receptor subtypes couple through G proteins to activation of phospholipase C