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Canonical Wnt Signaling in Differentiated Osteoblasts Controls Osteoclast Differentiation

✍ Scribed by Donald A. Glass II; Peter Bialek; Jong Deok Ahn; Michael Starbuck; Millan S. Patel; Hans Clevers; Mark M. Taketo; Fanxin Long; Andrew P. McMahon; Richard A. Lang; Gerard Karsenty


Book ID
116403837
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
993 KB
Volume
8
Category
Article
ISSN
1534-5807

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## Abstract The matricellular protein osteonectin, secreted protein acidic and rich in cysteine (SPARC, BM‐40), is the most abundant non‐collagenous matrix protein in bone. Matricellular proteins play a fundamental role in the skeleton as regulators of bone remodeling. In the skeleton, osteonectin