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Canonical Wnt Signaling in Osteoblasts Is Required for Osteoclast Differentiation

✍ Scribed by DONALD A. GLASS II; GERARD KARSENTY


Book ID
111479334
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
455 KB
Volume
1068
Category
Article
ISSN
0890-6564

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## Abstract The matricellular protein osteonectin, secreted protein acidic and rich in cysteine (SPARC, BM‐40), is the most abundant non‐collagenous matrix protein in bone. Matricellular proteins play a fundamental role in the skeleton as regulators of bone remodeling. In the skeleton, osteonectin