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Differential Gene Regulation by the Two Progesterone Receptor Isoforms in Human Breast Cancer Cells

โœ Scribed by Richer, J. K.; Jacobsen, B. M.; Manning, N. G.; Abel, M. G.; Wolf, D. M.; Horwitz, K. B.


Book ID
121731419
Publisher
The American Society for Biochemistry and Molecular Biology
Year
2001
Tongue
English
Weight
839 KB
Volume
277
Category
Article
ISSN
0021-9258

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Absence of estrogen receptor (ER) and progesterone receptor (PR) is the hallmark of most hormone-independent breast cancers. Previous studies demonstrated that reactivation of PR expression in hormone-independent MDA-MB-231 breast cancer cells enabled progesterone to suppress cell growth both in vit