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Progesterone regulates catechol-O-methyl transferase gene expression in breast cancer cells: Distinct effect of progesterone receptor isoforms

โœ Scribed by Salama A. Salama; Mohammad Jamaluddin; Raj Kumar; Memy H. Hassan; Ayman Al-Hendy


Book ID
116698060
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
452 KB
Volume
107
Category
Article
ISSN
0960-0760

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Absence of estrogen receptor (ER) and progesterone receptor (PR) is the hallmark of most hormone-independent breast cancers. Previous studies demonstrated that reactivation of PR expression in hormone-independent MDA-MB-231 breast cancer cells enabled progesterone to suppress cell growth both in vit