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Progesterone and levonorgestrel regulate expression of 17βHSD-enzymes in progesterone receptor positive breast cancer cell line T47D

✍ Scribed by Tove Sivik; Agneta Jansson


Book ID
116303400
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
487 KB
Volume
422
Category
Article
ISSN
0006-291X

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Progestin induction of 17β-hydroxysteroi
✍ M. Poutanen; V. Isomaa; K. Kainulainen; R. Vihko 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 French ⚖ 643 KB

## Abstract Steroid regulation of 17β‐hydroxysteroid dehydrogenase (17‐HSD) was studied in the T‐47D human breast‐cancer cell line, using a radioimmunoassay. In addition, 3 mRNA species (2.4, 1.4, and 0.9 kb) specific for the enzyme were shown to be present in these cells. All the synthetic progest