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Effect of Medrogestone on 17β-hydroxysteroid dehydrogenase activity in the hormone-dependent MCF-7 and T-47D human breast cancer cell lines

✍ Scribed by G.S Chetrite; C Ebert; F Wright; J.-C Philippe; J.R Pasqualini


Book ID
117669131
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
278 KB
Volume
68
Category
Article
ISSN
0960-0760

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Progestin induction of 17β-hydroxysteroi
✍ M. Poutanen; V. Isomaa; K. Kainulainen; R. Vihko 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 French ⚖ 643 KB

## Abstract Steroid regulation of 17β‐hydroxysteroid dehydrogenase (17‐HSD) was studied in the T‐47D human breast‐cancer cell line, using a radioimmunoassay. In addition, 3 mRNA species (2.4, 1.4, and 0.9 kb) specific for the enzyme were shown to be present in these cells. All the synthetic progest