✦ LIBER ✦

Differences in the binding of drugs to plasma proteins from newborn and adult man. II

✍ Scribed by H. Kurz; H. Michels; H. H. Stickel

Publisher: Springer
Year: 1977
Tongue: English
Weight: 288 KB
Volume: 11
Category: Article
ISSN: 0031-6970
DOI: 10.1007/bf00562941

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Differences in the binding of drugs to p

Differences in the binding of drugs to plasma proteins from newborn and adult man. I

✍ H. Kurz; A. Mauser-Ganshorn; H. H. Stickel 📂 Article 📅 1977 🏛 Springer 🌐 English ⚖ 366 KB

Endogenous metal binding proteins in rel

Endogenous metal binding proteins in relation to the differences in absorption and distribution of mercury in newborn and adult rats

✍ M. Webb; Daphne Holt 📂 Article 📅 1982 🏛 Springer-Verlag 🌐 English ⚖ 553 KB

Both in the ilatestinal copper complex and hepatic zinc-thionein of the newborn rat provide immediately available, high-affinity binding sites for Hg 2+. Retention of orally administered Hg 2+ in the gastrointestinal tract is much greater in the 5-day old rat than in the weanling and accounts for mo

Effect of halofenate on binding of vario

Effect of halofenate on binding of various drugs to human plasma proteins and on the plasma half-life of antipyrine in monkeys

✍ Howard B. Hucker; Susan C. Stauffer; Samuel E. White 📂 Article 📅 1972 🏛 John Wiley and Sons 🌐 English ⚖ 328 KB 👁 2 views

On the calculation of the concentration

On the calculation of the concentration dependence of drug binding to plasma proteins with multiple binding sites of different affinities: Determination of the possible variation of the unbound drug fraction and calculation of the number of binding sites of the protein

✍ Leonid M. Berezhkovskiy 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 161 KB 👁 1 views

The measurement of the unbound drug fraction in plasma is routinely performed at drug concentrations much less than that of plasma proteins. Commonly, the protein has several binding sites of different affinities. The obtained value of the unbound drug fraction does not yield the affinity of each bi

Application of ion-pair methods to drug

Application of ion-pair methods to drug extraction from biological fluids II: Quantitative determination of biguanides in biological fluids and comparison of protein binding estimates

✍ Edward R. Garrett; Josef Tsau; Peter H. Hinderling 📂 Article 📅 1972 🏛 John Wiley and Sons 🌐 English ⚖ 1003 KB

Endogenous and exogenous forms of the sa

Endogenous and exogenous forms of the same antigen are processed from different pools to bind MHC class II molecules in endocytic compartments

✍ Laura C. Bonifaz; Silvia Arzate; José Moreno 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 217 KB

The current studies were carried out to examine the basis for the differences in the antigenic peptides generated from exogenous and endogenous forms of hen egg white lysozyme (HEL). The role of different intracellular compartments in the generation and binding of HEL peptides derived from two endog