๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Effect of halofenate on binding of various drugs to human plasma proteins and on the plasma half-life of antipyrine in monkeys

โœ Scribed by Howard B. Hucker; Susan C. Stauffer; Samuel E. White

Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
328 KB
Volume
61
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Effects of penicillins on binding of phe
Effects of penicillins on binding of phenytoin to plasma proteins in vitro and in vivo
โœ K. Arimori; M. Nakano; M. Otagiri; K. Uekama ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 397 KB ๐Ÿ‘ 2 views

Effects of penicillins on the binding of phenytoin to plasma proteins were examined in vitro and in uivo. The results from in uitro studies showed that the penicillins including oxacillin and dicloxacillin were effective in displacing phenytoin from its binding sites. I n uivo, the total phenytoin c

On the calculation of the concentration
On the calculation of the concentration dependence of drug binding to plasma proteins with multiple binding sites of different affinities: Determination of the possible variation of the unbound drug fraction and calculation of the number of binding sites of the protein
โœ Leonid M. Berezhkovskiy ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 161 KB ๐Ÿ‘ 1 views

The measurement of the unbound drug fraction in plasma is routinely performed at drug concentrations much less than that of plasma proteins. Commonly, the protein has several binding sites of different affinities. The obtained value of the unbound drug fraction does not yield the affinity of each bi