✦ LIBER ✦

Differences in Active Site Gorge Dimensions of Cholinesterases Revealed by Binding of Inhibitors to Human Butyrylcholinesterase †

✍ Scribed by Saxena, Ashima; Redman, Ann M. G.; Jiang, Xuliang; Lockridge, Oksana; Doctor, B. P.

Book ID: 119978643
Publisher: American Chemical Society
Year: 1997
Tongue: English
Weight: 463 KB
Volume: 36
Category: Article
ISSN: 0006-2960
DOI: 10.1021/bi971425+

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Differences in active-site gorge dimensi

Differences in active-site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase

✍ Ashima Saxena; Ann M.G. Redman; Xuliang Jiang; Oksana Lockridge; B.P. Doctor 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 671 KB

Different effects of two peripheral anio

Different effects of two peripheral anionic site-binding ligands on acetylcholinesterase active-site gorge topography revealed by electron paramagnetic resonance

✍ Zoran Grubič; Anton Štalc; Marjeta Šentjurc; Slavko Pečar; Mary K. Gentry; Bhupe 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 548 KB

Rapid binding of a cationic active site

Rapid binding of a cationic active site inhibitor to wild type and mutant mouse acetylcholinesterase: Brownian dynamics simulation including diffusion in the active site gorge

✍ Sylvia Tara; Adrian H. Elcock; Paul D. Kirchhoff; James M. Briggs; Zoran Radic; 📂 Article 📅 1998 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 133 KB 👁 2 views

It is known that anionic surface residues play a role in the long-range electrostatic attraction between acetylcholinesterase and cationic ligands. In our current investigation, we show that anionic residues also play an important role in the behavior of the ligand within the active site gorge of ac

Structure–Activity Relationships and Bin

Structure–Activity Relationships and Binding Mode in the Human Acetylcholinesterase Active Site of Pseudo-Irreversible Inhibitors Related to Xanthostigmine

✍ Stefano Rizzo; Andrea Cavalli; Luisa Ceccarini; Manuela Bartolini; Federica Bell 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 679 KB

The two metal-binding sites of human ser

The two metal-binding sites of human serotransferrin and lactotransferrin differences in histidine coordination as revealed by EPR of cupric complexes

✍ Joël Mazurier; Jean-Marc Lhoste; Geneviève Spik; Jean Montreuil 📂 Article 📅 1977 🏛 Elsevier Science 🌐 English ⚖ 403 KB

Carbonic anhydrase inhibitors: Valdecoxi

Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II ‘selective’ inhibitor celecoxib

✍ Anna Di Fiore; Carlo Pedone; Katia D’Ambrosio; Andrea Scozzafava; Giuseppina De 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 331 KB