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Differences between familial and sporadic forms of colorectal cancer with DNA microsatellite instability

✍ Scribed by G. Dionigi; V. Bianchi; F. Villa; F. Rovera; L. Boni; M. Annoni; P. Castano; R. Dionigi


Book ID
113922212
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
218 KB
Volume
16
Category
Article
ISSN
0960-7404

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The reproducibility of microsatellite instability from different regions of the same sporadic colon cancer has not been addressed. We therefore microdissected and extracted DNA from three to nine separate regions of 13 highly unstable sporadic colon cancers. Each region was then evaluated by polymer