Glucagon and cAMP inhibit cholesterol 7α
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Kwang-Hoon Song; John Y. L. Chiang
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Article
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2005
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John Wiley and Sons
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English
⚖ 478 KB
The gene encoding cholesterol 7␣-hydroxylase (CYP7A1) is tightly regulated to control bile acid synthesis and maintain lipid homeostasis. Recent studies in mice suggest that bile acid synthesis is regulated by the fasted-to-fed cycle, and fasting induces CYP7A1 gene expression in parallel to the ind