The alkylation of the dianion of the title compound (2), readily prepared from (S)malic acid, with w-iodo-l-trimethylsilyl-2-alkynes (8a-c) occurs with high trans-selectivity with respect to the hydroxyl function. The productsTITa-c) cyclize in formic acid to enantiomerically pure azabicyclic allene
✦ LIBER ✦
Diastereoselectivity in the cyclization of 1-[2-(benzyloxymethyl)-3-butenyl]-5-ethoxy-2-pyrrolidinones
✍ Scribed by Johannes N. Zonjee; Henk de Koning; W.Nico Speckamp
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 956 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0040-4020
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