Stereoselectivity in the 1,3-dipolar cycloaddition of nitrones to 1-substituted 3,3-methylene-5,5-dimethyl-2-pyrrolidinones
✍ Scribed by L. Jaroškoá; L'. Fišera; I. Matejková; P. Ertl; N. Prónayová
- Publisher
- Springer Vienna
- Year
- 1994
- Tongue
- English
- Weight
- 760 KB
- Volume
- 125
- Category
- Article
- ISSN
- 0026-9247
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## Abstract Benzonitrile oxide cycloadds to the CC bond of substituted 4,5‐dihydro‐3‐methylene‐2(3__H__)‐furanones 1a–1g. Thus, (__E__)‐1a and (__E__)‐1b are converted into the corresponding isoxazolinespirodihydrofuranones (4__RS__,5__RS__)‐2a and (4__RS__,5__RS__)‐2b, and (__E__)‐1c is converted
## Abstract Substituted 4,5‐dihydro‐3‐methylene‐2(3__H__)‐furanones 1 react as dipolarophiles with diphenylnitrilimine to give the corresponding spiro[furan‐pyrazolin]ones 2. From the compound 1a, 1,3‐diphenyl‐7‐oxa‐1,2‐diazaspiro[4,4]non‐2‐en‐6‐one (2a) is formed. In the other cases, a primarily f