Diastereoselective triple radical cyclization of a bromomethyldimethylsilyl allyl ether
β Scribed by Andrew S. Kende; Michel Journet; Richard G. Ball; Nancy N. Tsou
- Book ID
- 103414205
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 230 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
Tandem radical cyclization of (E) and (Z) TMS-homopropargyl allyl brumomethyldimethylsilyl ethers is reported to provide an ail-cis substituted vinylcyclopentanol 5. Regio-and stereospecificity are discussed.
Regio-and Stereospecificity in Radical Cascade Cyclizations of TMS-Alcyne Containing Allyl Bromomethyldimethylsilyl Ethers. -Tandem radical cyclization of the racemic (E)-silane (I) yields the all-cis substituted vinylcyclopentanol (II) as an isoprostanoid precursor together with minor amounts of t
5-Endo-trig Radical Cyclizations of Bromomethyldimethylsilyl Diisopropylpropargylic Ethers. A Highly Diastereoselective Access to Functionalized Cyclopentanes. -The title ethers (I), (V) and (VIII) undergo a radical-induced 5-exo-dig cyclization-diastereoselective 1,5-hydrogen transfer-5-endo-trig