Diastereoselective synthesis of β-(3,4,6-tri-O-benzyl-2-deoxy-β-D-galactopyranosyl)-N-tert-butoxycarbonyl-D-alanine
✍ Scribed by Albrecht Lieberknecht; Helmut Griesser; Bernd Krämer; Rodolfo D. Bravo; Pedro A. Colinas; Raúl J. Grigera
- Book ID
- 104209403
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 449 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Recent years have seen a remarkable surge of interest in the study of U-Lfucosyltransferases. Of these L-fucosyltransferases, the enzyme (143)~a+fucosyltransferase has attracted a great deal of clinical interest as a potential tumor marker. This enzyme catalyzes the transfer of an L-fucosyl group f
Sequential tritylation, benzoylation, and detritylation of methyl 3-deoxy-3fluoro-AD-galactop~~oside gave crystalline methyl 2,4-di-O-benzoyl-3-deoxy-3-~uoro-ED-gala~opyr~oside (9), which was used as the initial nucleophile in the synthesis of the target otigosaccha~de (16). Treatment of 9 with 2,3,