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Diastereoselective synthesis of 2,3,4,5-tetrasubstituted isoxazolidines via 1,3-dipolar cycloaddition

✍ Scribed by Vellaisamy Sridharan; Shanmugam Muthusubramanian; Shanmugaperumal Sivasubramanian; Kurt Polborn

Book ID
108282702
Publisher
Elsevier Science
Year
2004
Tongue
French
Weight
340 KB
Volume
60
Category
Article
ISSN
0040-4020

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Diastereoselective synthesis of nicotine
Diastereoselective synthesis of nicotine derivatives via 1,3-dipolar cycloaddition reactions
✍ Mehdi Ghandi; Abuzar Taheri; Alireza Abbasi πŸ“‚ Article πŸ“… 2010 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 339 KB

## Abstract magnified image A simple diastereoselective route to nicotine derivatives is presented. The one‐pot three component 1,3‐dipolar cycloaddition reaction of the KnΓΆevenagel adducts of a number of aromatic aldehydes and malononitrile with an azomethine ylide derived __in situ__ from pyridin