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Diastereoselective Mukaiyama-Michael reaction of O,S-ketene silyl acetal

โœ Scribed by Yukihiro Fujita; Junzo Otera; Shunichi Fukuzumi


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
624 KB
Volume
52
Category
Article
ISSN
0040-4020

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๐Ÿ“œ SIMILAR VOLUMES


Mukaiyama-Michael reaction of cyclic ket
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Michael reaction of macrocyclic ketene silyl acetals or a-enones occurs smoothly under electron transfer conditions while the reaction of 6-membored analogs is more sluggish, indicating the importance of the ring flexibility to allow the a,~-carbon-carbon bonds of both reaction components to rotate

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## The structure of &[[I -(I .I -dimethylethoxy)-1 -propenyl]oxyl(l,l -dimethylethyI)diphenyl silane (1). as determined by single crystal x-ray diffraction analysis. is described.

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โœ Yukihiro Fujita; Shunichi Fukuzumi; Junzo Otera ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 155 KB

SmI2-promoted conjugate reduction of ~-unsaturated esters and ketones txoceeds in a manner quite similar to Mukaiyama-Michael reaction of ketene silyl acetal. The more substituted